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Ann Thorac Surg 1977;23:52-57
© 1977 The Society of Thoracic Surgeons


Articles

Oxygen Consumption during Surface-Induced Deep Hypothermia under Halothane Anesthesia

Takeshi Ishitoya, M.D., Shigekazu Sato, M.D., Giuseppe DiBenedetto, M.D., Vittorio Vanini, M.D., Hitoshi Mohri, M.D.*, K. Alvin Merendino, M.D., David H. Dillard, M.D.

Division of Cardiothoracic Surgery, Department of Surgery, University Hospital, University of Washington School of Medicine, Seattle, WA.

Accepted for publication March 9, 1976.

* Address reprint requests to Dr. Mohri, Department of Surgery RF-25, University Hospital, Seattle, WA 98195.

The effect of halothane-100% oxygen anesthesia on oxygen consumption was studied in 10 dogs subjected to surface-induced deep hypothermia with 30 minutes of circulatory arrest. The results were compared with previous oxygen consumption data under ether-100% oxygen anesthesia.

Low cardiac output, especially during the rewarming period, low Pa02, and a large arteriovenous oxygen difference during rewarming were significantly different in the halothane group, despite identical oxygen consumption in both groups. These differences could not elucidate the exact cause of postoperative motor disturbances associated with 30 minutes of circulatory arrest in the halothane group. The possibility that there was higher oxygen consumption under halothane anesthesia is discussed.




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