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Ann Thorac Surg 1977;23:26-31
© 1977 The Society of Thoracic Surgeons

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Articles

Mitral Valve Replacement with the Modified University of Cape Town (UCT) Prosthesis: Clinical and Hemodynamic Results

Department of Surgery, Section of Thoracic and Cardiovascular Surgery, and the Department of Internal Medicine, Section of Cardiovascular Disease, Lahey Clinic Foundation and New England Deaconess Hospital, Boston, MA.

Accepted for publication April 23, 1976.

^* Address reprint requests to Dr. Ellis, Lahey Clinic Foundation, 605 Commonwealth Ave, Boston, MA 02215.

Mitral valve replacement with the modified University of Cape Town prosthesis was performed in 42 patients. In 35 the procedure was an isolated one, and the hospital mortality was 6%. The late survival rate was 60%, half of the late deaths being the result of thromboembolism or complications of anticoagulant therapy. The incidence of hemolysis was low, and hemodynamic results demonstrated improvement in cardiac index and lowering of pulmonary artery pressure, pulmonary artery wedge pressure, pulmonary arteriolar resistance, and transvalvular mean gradients. However, the calculated prosthetic valve orifice area was lower than the measured area. Because of complications of thromboembolism, the high incidence of late deaths, and high transvalvular gradients, this prosthetic valve is no longer used in patients requiring mitral valve replacement.

This article has been cited by other articles:

				I. F. Galvin, N. J. Buckels, N. P. Campbell, and J. Cleland Long-Term function in University of Cape Town prostheses in the tricuspid position Ann. Thorac. Surg., September 1, 1991; 52(3): 552 - 554. [Abstract] [PDF]