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Ann Thorac Surg 1976;22:524-527
© 1976 The Society of Thoracic Surgeons

Articles

Surgical versus Medical Treatment for Stable Angina Pectoris: Prospective Randomized Study with 1- to 4-Year Follow-up

Gene A. Guinn, M.D.*, Virendra S. Mathur, M.D.

From the Departments of Surgery and Cardiology, Baylor College of Medicine, Houston, TX

* Address reprint requests to Dr. Guinn, Chief, Thoracic and Cardiovascular Surgery, Veterans Administration Hospital, Houston, TX 77031

A prospective randomized study to evaluate aortocoronary bypass was done on 116 patients (56 surgical, 60 medical) who had documented coronary artery disease (70% luminal obstruction in a major artery). The two groups were similar in age and risk factors. All patients have been followed for a mean of 34 months, and recatheterization has been done in 106 of the survivors. Important results show that although most patients in both groups are improved, more surgical patients are asymptomatic (68 vs 8%). Exercise tolerance was better in the surgical group (+94% vs +43%). There was significantly greater evidence of preinfarction angina in the medical group (p < 0.02), but survival was similar.




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