ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Tan, A. J. K.
Right arrow Articles by Holt, D. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tan, A. J. K.
Right arrow Articles by Holt, D. L.

Ann Thorac Surg 1976;22:188-194
© 1976 The Society of Thoracic Surgeons


Articles

The Effects of Sterilization and Storage Treatments on the Stress-Strain Behavior of Aortic Valve Leaflets

A.J.K. Tan, M.E., D.L. Holt, Sc.D.*

From the School of Engineering, University of Auckland, Auckland, New Zealand.

Accepted for publication January 7, 1975.

* Address reprint requests to Dr. Holt, 141 W Newton St, Boston, MA 02118.

An investigation was made of the feasibility of using tensile tests to detect alterations in the molecular structure of aortic valve tissue brought about by sterilizing or storage treatments. Stressstrain tests were carried out on fresh valve leaflets from pigs and repeated with the same specimens after specified sterilization or storage treatments. It was found that the stress at a given strain was increased by treatment with ethylene oxide, buffered formalin, and tissue culture solution and decreased by treatment with antibiotics. The least change was with tissue culture solution and antibiotics.

It has been suggested that the best method of allograft sterilization should involve minimal structural alteration to the collagen and elastic components of the tissue. Thus, treatment with tissue culture solution and antibiotics seems appropriate.







HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1976 by The Society of Thoracic Surgeons.