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Ann Thorac Surg 1976;21:508-512
© 1976 The Society of Thoracic Surgeons

Articles

Local Deep Hypothermia for Combined Valvular and Coronary Heart Disease

Dennis F. Pupello, M.D.*, Richard H. Blank, M.D., Luis N. Bessone, M.D., Richard G. Connar, M.D., Leffie M. Carlton, Jr., M.D.

Division of Thoracic and Cardiovascular Surgery, University of South Florida School of Medicine, Tampa, FL

* Address reprint requests to Dr. Pupello, 1 Davis Blvd, Tampa, FL 33606

Local deep hypothermia was utilized as the sole method of myocardial protection in 113 consecutive aortic valve replacements. Thirty-six patients had simultaneous revascularization, mitral valve replacement, tricuspid valve replacement, or a combination of these. In follow-up for as long as 36 months there have been 3 hospital deaths (2.6%), all occurring in the group having isolated aortic valve replacement. No hospital deaths occurred among patients undergoing a combined procedure.

This experience suggests that local hypothermia provides adequate myocardial protection during periods of obligatory anoxia, even in the presence of associated coronary atherosclerosis, and that combined correction of valvular and coronary disease is feasible and is indicated in properly selected patients.




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