ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Issei Kiso
Hisamichi Baba
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kiso, I.
Right arrow Articles by Kantrowitz, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kiso, I.
Right arrow Articles by Kantrowitz, A.

Ann Thorac Surg 1976;21:203-208
© 1976 The Society of Thoracic Surgeons

Articles

An Extravascular Left Ventricular Assist Device

Issei Kiso, M.D., C.A. Baechler, Ph.D., Osami Hamada, M.D., Gerald Mandell, M.D., Hisamichi Baba, M.D., Adrian Kantrowitz, M.D.*

From the Department of Cardiovascular and Thoracic Surgery, Sinai Hospital of Detroit, and the Department of Physiology, Wayne State University Medical School, Detroit, MI.

Accepted for publication September 16, 1975.

* Address reprint requests to Dr. Kantrowitz, Department of Cardiovascular and Thoracic Surgery, 6767 W Outer Dr, Detroit, MI 48235

The hemodynamic efficacy and prosthesis-vessel interaction of a pneumatically activated circulatory assist device was investigated in 12 acute and 12 chronic studies in dogs. A poly-urethane balloon encased in Dacron-velour cloth was fastened to the descending thoracic aorta with a spiral wrapping of Dacron graft material. Diastolic augmentation was provided by rhythmic inflation and deflation of the balloon. Hemodynamic results, based on 5 dogs with experimental myocardial ischemia, showed that left ventricular systolic peak pressure decreased by 8.2 ± 1.9%, cardiac output increased by 13.1 ± 2.8%, and circumflex coronary artery flow rose by 17.5 ± 2.5%.

In the chronic experiments the prosthesis was asynchronously but continuously activated from one to sixteen weeks at 74 cycles per minute. Postmortem examination of the implantation site in all 12 dogs showed that necrosis had developed but was limited to the outer half of the medial layer beneath the pumping chamber and that the aortic wall was compressed to about 70% of its original thickness.

Although the method described represents a simple form of providing ventricular assistance, its applicability for long-term circulatory support remains to be evaluated.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1976 by The Society of Thoracic Surgeons.