HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Look, A. T. Articles by Bates, T. R. Search for Related Content PubMed PubMed Citation Articles by Look, A. T., Jr. Articles by Bates, T. R., Jr.

Ann Thorac Surg 1975;20:571-580
© 1975 The Society of Thoracic Surgeons

---

Articles

The Effect of Natural and Surgically Constructed Aortopulmonary Shunts on Hemodynamic Function in Tetralogy of Fallot

University of Michigan Medical School and the Department of Mechanical Engineering, the University of Michigan, Ann Arbor, Mich.

Accepted for publication April 23, 1975.

^* Address reprint requests to Dr. Look, Department of Pediatrics, F-2230 Mott Hospital, Ann Arbor, Mich. 48104

A hemodynamic model has been developed for the patient with tetralogy of Fallot. Equations representing the circulatory flow pattern and oxygen balance in this disease were incorporated into a computer program. With the computer model it is possible to simulate the effect of natural and surgically constructed aortopulmonary shunt flow on hemodynamic function in tetralogy of Fallot.

Graphic representations of the computer output are presented which show how aortopulmonary shunt flow influences the physiology of exercise and hypoxic episodes. An explanation is advanced for the lack of correlation between resting arterial oxygen saturation and the incidence of hypoxic episodes. The model demonstrates the effect of surgical aortopulmonary shunts in eliminating hypoxic spells.