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The Annals of Thoracic Surgery, Vol 20, 446-455, Copyright © 1975 by The Society of Thoracic Surgeons


ARTICLES

Local cardiac hypothermia for myocardial protection during correction of congenital heart disease

JJ Lamberti, LH Cohn, H Laks, NS Braunwald, JJ Collins Jr and AR Castaneda

Eighty-eight operations for correction of intracardiac congenital heart defects were performed using local cardiac hypothermia for protection of the ischemic myocardium. Twenty-six patients underwent repair of tetralogy of Fallot, 23 had patch closure of ventricular septal defect, 24 had correction of various types of congenital aortic stenosis, and 15 were operated upon for other complex lesions. The overall operative mortality was 5.6%. Ischemia times ranged from 9 to 119 minutes (mean, 48 minutes). Ischemic arrest protected by local cardiac hypothermia provides an optimal operative field, permitting repair of uncomplicated intracardiac defects in a precise, unhurried manner. No hemodynamic abnormalities attributable to the technique were encountered.


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B. Ostadal, I. Ostadalova, and N. S. Dhalla
Development of Cardiac Sensitivity to Oxygen Deficiency: Comparative and Ontogenetic Aspects
Physiol Rev, July 1, 1999; 79(3): 635 - 659.
[Abstract] [Full Text] [PDF]




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Copyright © 1975 by The Society of Thoracic Surgeons.