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Ann Thorac Surg 1975;20:433-445
© 1975 The Society of Thoracic Surgeons

Articles

Experimentally Reversed Pulmonary Blood Flow

Implications for the Surgical Management of Complex Forms of Congenital Heart Disease

Richard E. Clark, M.D.*, Robert C. McKnight, M.D., John M. Kissane, M.D., Clarence S. Weldon, M.D.

From the Division of Cardiothoracic Surgery and the Departments of Radiology and Pathology, Washington University School of Medicine, St. Louis, Mo.

* Address reprint requests to Dr. Clark, Division of Cardiothoracic Surgery, Washington University School of Medicine, 4960 Audubon Ave., St. Louis, Mo. 63110

Blood flow to the right lung was reversed in 28 dogs, 14 of which survived more than 1 month. Four successful long-term survivors (1 year to 4 years 7 months) were repeatedly studied by cardiac catheterization, angiography, and ventilation/perfusion scans as well as hemodynamically when they were killed. Hemodynamics and gas transfer were normal up to 41/2 years after the procedure, and the histology of the right lung was essentially normal.

The application of reversed pulmonary blood flow is proposed in the surgical management of forms of congenital heart disease in which the right ventricle is diminutive. The procedure consists of repartitioning of the atria to allow venous blood to flow into the lung through the pulmonary veins and exit to the left atrium through the pulmonary artery.




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A. C. Kralios
Feasibility of Closed-Chest Left Ventricular Bypass Using Unilateral Retrograde Transpulmonary Flow
Ann. Thorac. Surg., August 1, 1977; 24(2): 162 - 169.
[Abstract] [PDF]


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Copyright © 1975 by The Society of Thoracic Surgeons.