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Ann Thorac Surg 1975;20:299-307
© 1975 The Society of Thoracic Surgeons

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Articles

The Use of Forane Anesthesia for Surface-Induced Deep Hypothermia

From the Department of Surgery, the Division of Cardiothoracic Surgery, and the Department of Anesthesiology of the University Hospital, University of Washington School of Medicine, Seattle, Wash.

Accepted for publication March 25, 1975.

^* Address reprint requests to Dr. Mohri, Department of Surgery, RF-25, University Hospital, Seattle, Wash. 98195

The effects of Forane anesthesia for deep surface hypothermia with 30 minutes of total circulatory occlusion were evaluated. With 100% O₂ 6 of 7 dogs developed motor disorders postoperatively, while 3 of 5 with 98% O₂/2% CO₂ and none with 95% O₂/5% CO₂ developed motor disorders.

Cooling was uneventful except for 1 episode of ventricular fibrillation in the 5% CO₂ group at 23°C. Resuscitation was easy, but the early rewarming period was characterized by repeated episodes of ventricular fibrillation and delayed recovery of cardiac function, especially in the 100% O₂ group.

Blood lactate levels remained low during cooling and gradually increased during rewarming in all groups, with the highest levels in the 100% O₂ group and the lowest in the 5% CO₂ group.

It is concluded that Forane can be used for surface hypothermia with 30 minutes' circulatory occlusion when administered in 95% O₂/5% CO₂. A comparison of these results with previously reported series indicates that Forane is inferior to ether but may be superior to halothane for surface hypothermia.

This article has been cited by other articles:

				K. Haneda, M. P. Sands, R. Thomas, S. H. Merrick, E. A. Hessel II, and D. H. Dillard Circulatory Dynamics during Surface-Induced Hypothermia under Halothane-Ether Azeotrope Anesthesia Ann. Thorac. Surg., March 1, 1982; 33(3): 258 - 266. [Abstract] [PDF]

				M. P. Sands, D. H. Dillard, E. A. Hessel II, and D. W. Miller Jr Improved Anesthesia for Deep Surface-Induced Hypothermia: The Halothane-Diethyl Ether Azeotrope Ann. Thorac. Surg., February 1, 1980; 29(2): 123 - 129. [Abstract] [PDF]