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Ann Thorac Surg 1975;20:91-94
© 1975 The Society of Thoracic Surgeons


Articles

Metabolic Arrest of the Ischemic Heart

G. Frank O. Tyers, M.D.

From the Department of Surgery, The Pennsylvania State University College of Medicine and The Milton S. Hershey Medical Center, Hershey, Pa. 17033.

Procaine, hypocalcemia, magnesium, fluoride, adrenochrome, and tetrodotoxin have been used to induce metabolic arrest of the heart and increase its tolerance to ischemia. Prolonged periods of ischemic cardiac arrest without measurable deterioration of cardiac function are possible. The application of these techniques in the repair of intracardiac lesions deserves further study.




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