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Ann Thorac Surg 1975;19:537-539
© 1975 The Society of Thoracic Surgeons

Articles

Complications Associated with Membrane Lung Support by Venoarterial Perfusion

Jack L. Ratliff, M.D.*, J. Donald Hill, M.D., Robert J. Fallat, M.D., James Parrot, M.D., Harvey J. Tucker, M.D.

Institutes of Medical Sciences and the Bothin Heart Research Laboratory, and the Department of Cardiovascular Surgery, Pacific Medical Center, San Francisco, Calif

Accepted for publication December 18, 1974.

* Address reprint requests to Dr. Ratliff, 2009 Buchanan St., San Francisco, Calif. 94115

A series of patients supported with long-term venoarterial perfusion is presented. Gas exchange was achieved with a membrane oxygenator at flows usually in excess of 50% of the patient's baseline cardiac output. Perfusions were maintained for 7 to 12 days. Two major complications were encountered: thromboembolic myocardial infarction and liquefaction necrosis of the lung. Possible etiologies and suggestions for prevention are discussed.




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