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The Annals of Thoracic Surgery, Vol 19, 521-528, Copyright © 1975 by The Society of Thoracic Surgeons
HW Bender Jr, RD Fisher, SL Faulkner and GC Friesinger
In eighty-eight patients with arteriographic findings of obstructive
coronary artery disease and the clinical picture of unstable angina
pectoris, a decision on operative or nonoperative management was made by
the attending physician. Fifty-three of them subsequently underwent
aortocoronary saphenous vein bypass grafting and 35 were continued on a
program of medical therapy. A marked difference in the course after the
first 30 days was noted, with most of the surgically managed patients being
either asymptomatic or greatly improved following coronary artery bypass.
Two-thirds of the medically treated patients had persistent severe angina
pectoris and non was asymptomatic in a follow-up period averaging 20
months. There were 2 late deaths in the medical group and none in the
surgical group. These findings indicate that coronary artery bypass
operations can be performed with low risk during the unstable phase of
coronary artery disease and that relief of angina can be anticipated. In
contrast, nonoperative management of unstable coronary artery disease
carries an appreciable risk of death or myocardial infarction, and the
majority of patients treated nonoperatively continue to experience angina.
ARTICLES
Unstable coronary artery disease: comparison of medical and surgical treatment
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