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Ann Thorac Surg 1975;19:397-405
© 1975 The Society of Thoracic Surgeons

Articles

Exercise Tolerance After Repair of Tetralogy of Fallot

Denise J. Strieder, M.D.*, Kalim Aziz, M.D., Alla G. Zaver, M.D., Kenneth E. Fellows, M.D.

From the Departments of Cardiology (Pulmonary Laboratory) and Radiology, Children's Hospital Medical Center, and the Departments of Pediatrics and Radiology, Harvard Medical School, Boston, Mass.

Accepted for publication December 4, 1974.

* Address reprint requests to Dr. Strieder, Children's Hospital Medical Center, Boston, Mass. 02115.

Twelve patients who had undergone complete repair of tetralogy of Fallot at ages ranging from 8 to 27 years were studied for exercise tolerance several years later. Work performance ranged from 58 to 130% of that predicted. Increased physiological dead space and alveolar-arterial Po2 difference at exercise suggested pulmonary vascular disease, which was confirmed in 1 patient by pulmonary angiography. Exercise tolerance decreased with increasing age at time of repair, underlining the desirability of early corrective operation.




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