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Ann Thorac Surg 1974;18:516-530
© 1974 The Society of Thoracic Surgeons

Articles

Hemotensiometry: A New Technique for the Study of Hemostasis in Open-Heart Surgery

John H. Altshuler, M.D.*, Thomas L. Altshuler, Ph.D., William L. Halseth, M.D., Donald P. Elliott, M.D., Edith B. Roos, M.D., Ernest Feiler, M.D.

Departments of Medicine, Pathology, and Surgery, University of Colorado School of Medicine, Denver, Colo., and Fitchburg State College, Fitchburg, Mass

* Address reprint requests to Dr. John H. Altshuler, 3705 E. Colfax Ave., Denver, Colo. 80206

Hemotensiometry is a new technique utilizing the principle of gas activation of clotting factors in vitro. The method has proved beneficial in open-heart operations because of its ability to determine the status of heparin anticoagulation and protamine neutralization rapidly and accurately at any given instant. Measurement of heparin levels takes about 5 minutes and requires 1.5 ml. of blood per assay. Prolonged hemorrhage from inadequate heparin neutralization may thus be prevented with the use of the Hemometer and hemotensiometric methods which we have developed.




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