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Ann Thorac Surg 1973;15:354-363
© 1973 The Society of Thoracic Surgeons


Articles

In Vivo Determination of Renal Tissue Oxygenation During Pulsatile and Nonpulsatile Left Heart Bypass

N.D. Mukherjee, M.D., A.V. Beran, B.S., J. Hirai, M.D., A. Wakabayashi, M.D., D.R. Sperling, M.D., W.F. Taylor, M.D., J.E. Connolly, M.D.*

From the Departments of Surgery and Pediatrics, University of California, Irvine, College of Medicine, Irvine, Calif

Accepted for publication November 27, 1972.

* Address reprint requests to Dr. Connolly, Department of Surgery, University of California, Irvine, College of Medicine, Irvine, Calif. 92664

Data favoring pulsatile over nonpulsatile left heart bypass are conflicting. To study this problem, renal cortical and medullary tissue oxygen availability (O2a) and total renal oxygen flow were compared with total renal oxygen consumption during four hours of pulsatile and nonpulsatile bypass in dogs. Although there was no difference in renal tissue O2a during the first two hours, thereafter the decrease in renal O2a was greater during nonpulsatile bypass; total renal blood flow was greater with pulsatile bypass, and at the given renal oxygen flow, renal oxygen consumption was greater during pulsatile bypass. These data, along with previous work, support the superiority of pulsatile bypass.




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